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Orthologous genes in OrthoFinder**

Species Gene Description
 gma-u.5   DHFR-TS   bifunctional dihydrofolate reductase-thymidylate synthase 
 gma-r.7   DHFR-TS   bifunctional dihydrofolate reductase-thymidylate synthase 
 gma-m.5   DHFR-TS   bifunctional dihydrofolate reductase-thymidylate synthase 
 gma-u.5   100786311   bifunctional dihydrofolate reductase-thymidylate synthase 
 gma-u.5   100786329   bifunctional dihydrofolate reductase-thymidylate synthase-like protein 
 mtr-u.5   25495385   bifunctional dihydrofolate reductase-thymidylate synthase 
 mtr-u.5   11440565   bifunctional dihydrofolate reductase-thymidylate synthase 
 mtr-u.5   11415341   bifunctional dihydrofolate reductase-thymidylate synthase 
 ppo-u.5   7456362   bifunctional dihydrofolate reductase-thymidylate synthase 1 
 ppo-u.5   7470002   bifunctional dihydrofolate reductase-thymidylate synthase 1 
 ath-u.5   THY-1   thymidylate synthase 1 
 ath-u.5   THY-2   thymidylate synthase 2 
 vvi-u.5   100267529   bifunctional dihydrofolate reductase-thymidylate synthase 
 vvi-u.5   100255872   putative bifunctional dihydrofolate reductase-thymidylate synthase 
 sly-u.5   101267455   bifunctional dihydrofolate reductase-thymidylate synthase-like protein 
 osa-u.5   4350527   bifunctional dihydrofolate reductase-thymidylate synthase 
 osa-u.5   9271078   putative bifunctional dihydrofolate reductase-thymidylate synthase 
 zma-u.5   541707   bifunctional dihydrofolate reductase-thymidylate synthase 
 zma-u.5   100286018   uncharacterized LOC100286018 

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Top 50 coexpressed genes to DHFR-TS (gma-u.5 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)

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Top 50 enrichment test to DHFR-TS (gma-u.5 coexpression data)

CoexMap"547833"


gmaDHFR-TS | Entrez gene ID : 547833      
Species gma mtr ppo ath vvi sly osa zma sbi nta bra cre hvu cit bdi sot tae bna ghi
Paralog 5 3 2 2 2 1 2 2 0 0 0 0 0 0 0 0 0 0 0
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CoexMap
Chloroplast
Nucleus

functional annotation
KEGG gmx00240 [list] [network] Pyrimidine metabolism (120 genes)
gmx00670 [list] [network] One carbon pool by folate (72 genes)
gmx00790 [list] [network] Folate biosynthesis (57 genes)
gmx01232 [list] [network] Nucleotide metabolism (148 genes)
gmx01240 [list] [network] Biosynthesis of cofactors (475 genes)
GO BP
GO:0006231 [list] [network] dTMP biosynthetic process  (4 genes)  IEA  
GO:0046654 [list] [network] tetrahydrofolate biosynthetic process  (10 genes)  IEA  
GO:0006730 [list] [network] one-carbon metabolic process  (44 genes)  IEA  
GO CC
GO:0005739 [list] [network] mitochondrion  (1058 genes)  IEA  
GO:0005829 [list] [network] cytosol  (1702 genes)  IEA  
GO MF
GO:0004146 [list] [network] dihydrofolate reductase activity  (4 genes)  IEA  
GO:0004799 [list] [network] thymidylate synthase activity  (4 genes)  IEA  
Protein NP_001238644.2 [sequence] [blastp]
XP_006581064.1 [sequence] [blastp]
XP_006581065.1 [sequence] [blastp]
Subcellular
localization
wolf
chlo 3,  cyto 3,  nucl 1,  cyto_pero 1,  cyto_E.R. 1  (predict for NP_001238644.2)
chlo 9,  nucl 1,  mito 1  (predict for XP_006581064.1)
chlo 9,  nucl 1,  mito 1  (predict for XP_006581065.1)
Subcellular
localization
TargetP
other 8  (predict for NP_001238644.2)
chlo 6  (predict for XP_006581064.1)
chlo 6  (predict for XP_006581065.1)
Gene expression
All samples [Expression pattern]
Tissue specificity*
Show Coexpressed Genes
Gene Function KEGG Entrez
Gene
ID		 Other ID Link Target Reference

gma-u.5
for
DHFR-TS

.
gma-r.7
for
DHFR-TS

.
gma-m.5
for
DHFR-TS

.
gma-u.5
for
100786311

.
gma-u.5
for
100786329

.
mtr-u.5
for
25495385

.
mtr-u.5
for
11440565

.
mtr-u.5
for
11415341

.
ppo-u.5
for
7456362

.
ppo-u.5
for
7470002

.
ath-u.5
for
THY-1

.
ath-u.5
for
THY-2

.
vvi-u.5
for
100267529

.
vvi-u.5
for
100255872

.
sly-u.5
for
101267455

.
osa-u.5
for
4350527

.
osa-u.5
for
9271078

.
zma-u.5
for
541707

.
zma-u.5
for
100286018

.


Ortholog ID: 4675
Species ath ath gma gma sly osa osa zma zma bra bra vvi vvi ppo ppo mtr mtr tae tae hvu ghi ghi bna bna cre sbi sot cit bdi nta nta
Symbol THY-1 THY-2 LOC100786311 LOC100786329 LOC101267455 LOC9271078 LOC4350527 LOC541707 LOC100286018 LOC103862355 LOC103836808 LOC100267529 LOC100255872 LOC7456362 LOC7470002 LOC11415341 LOC25495385 LOC123190811 LOC123054960 LOC123428176 LOC107928896 LOC107927990 LOC106393759 LOC106406829 CHLRE_17g715900v5 LOC8068714 LOC102593228 LOC102610005 LOC100832991 LOC107794251 LOC107792811
Function* thymidylate synthase 1 thymidylate synthase 2 bifunctional dihydrofolate reductase-thymidylate synthase bifunctional dihydrofolate reductase-thymidylate synthase-like protein bifunctional dihydrofolate reductase-thymidylate synthase-like protein putative bifunctional dihydrofolate reductase-thymidylate synthase bifunctional dihydrofolate reductase-thymidylate synthase bifunctional dihydrofolate reductase-thymidylate synthase uncharacterized LOC100286018 bifunctional dihydrofolate reductase-thymidylate synthase 2-like bifunctional dihydrofolate reductase-thymidylate synthase 2 bifunctional dihydrofolate reductase-thymidylate synthase putative bifunctional dihydrofolate reductase-thymidylate synthase bifunctional dihydrofolate reductase-thymidylate synthase 1 bifunctional dihydrofolate reductase-thymidylate synthase 1 bifunctional dihydrofolate reductase-thymidylate synthase bifunctional dihydrofolate reductase-thymidylate synthase putative bifunctional dihydrofolate reductase-thymidylate synthase putative bifunctional dihydrofolate reductase-thymidylate synthase putative bifunctional dihydrofolate reductase-thymidylate synthase bifunctional dihydrofolate reductase-thymidylate synthase 1 bifunctional dihydrofolate reductase-thymidylate synthase bifunctional dihydrofolate reductase-thymidylate synthase 2-like bifunctional dihydrofolate reductase-thymidylate synthase 1 uncharacterized protein bifunctional dihydrofolate reductase-thymidylate synthase bifunctional dihydrofolate reductase-thymidylate synthase-like bifunctional dihydrofolate reductase-thymidylate synthase-like putative bifunctional dihydrofolate reductase-thymidylate synthase bifunctional dihydrofolate reductase-thymidylate synthase bifunctional dihydrofolate reductase-thymidylate synthase-like
Coexmap

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Coexpression

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KEGG Info
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
ath00240 Pyrimidine metabolism 2
ath00670 One carbon pool by folate 2
ath00790 Folate biosynthesis 2
ath01232 Nucleotide metabolism 2
ath01240 Biosynthesis of cofactors 2
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
ath00240 Pyrimidine metabolism 2
ath00670 One carbon pool by folate 2
ath00790 Folate biosynthesis 2
ath01232 Nucleotide metabolism 2
ath01240 Biosynthesis of cofactors 2
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
gma04626 Plant-pathogen interaction 2
gma00240 Pyrimidine metabolism 2
gma00670 One carbon pool by folate 2
gma00790 Folate biosynthesis 2
gma01232 Nucleotide metabolism 2
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
gma00670 One carbon pool by folate 3
gma00240 Pyrimidine metabolism 2
gma00790 Folate biosynthesis 2
gma01232 Nucleotide metabolism 2
gma01240 Biosynthesis of cofactors 2
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
sly03050 Proteasome 3
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
osa03010 Ribosome 17
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
osa00670 One carbon pool by folate 2
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
zma00240 Pyrimidine metabolism 4
zma00670 One carbon pool by folate 4
zma00790 Folate biosynthesis 4
zma01232 Nucleotide metabolism 4
zma01240 Biosynthesis of cofactors 4
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
zma00970 Aminoacyl-tRNA biosynthesis 5
zma00240 Pyrimidine metabolism 4
zma00670 One carbon pool by folate 4
zma00790 Folate biosynthesis 4
zma01232 Nucleotide metabolism 4
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
bra01240 Biosynthesis of cofactors 2
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
bra00970 Aminoacyl-tRNA biosynthesis 3
bra03015 mRNA surveillance pathway 3
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
vvi00190 Oxidative phosphorylation 2
vvi00561 Glycerolipid metabolism 2
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
ppo00670 One carbon pool by folate 3
ppo00270 Cysteine and methionine metabolism 2
ppo04981 Folate transport and metabolism 2
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mtr01240 Biosynthesis of cofactors 4
mtr00240 Pyrimidine metabolism 2
mtr00670 One carbon pool by folate 2
mtr00790 Folate biosynthesis 2
mtr01232 Nucleotide metabolism 2
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mtr01240 Biosynthesis of cofactors 3
mtr00564 Glycerophospholipid metabolism 2
mtr00240 Pyrimidine metabolism 2
mtr00670 One carbon pool by folate 2
mtr00790 Folate biosynthesis 2
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
tae03030 DNA replication 9
tae03440 Homologous recombination 6
tae03410 Base excision repair 5
tae03420 Nucleotide excision repair 5
tae03430 Mismatch repair 5
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
tae01240 Biosynthesis of cofactors 4
tae00240 Pyrimidine metabolism 3
tae00670 One carbon pool by folate 3
tae00790 Folate biosynthesis 3
tae01232 Nucleotide metabolism 3
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hvu03010 Ribosome 5
hvu03008 Ribosome biogenesis in eukaryotes 2
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
ghi00240 Pyrimidine metabolism 4
ghi00670 One carbon pool by folate 4
ghi00790 Folate biosynthesis 4
ghi01232 Nucleotide metabolism 4
ghi01240 Biosynthesis of cofactors 4
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
ghi00240 Pyrimidine metabolism 4
ghi00670 One carbon pool by folate 4
ghi00790 Folate biosynthesis 4
ghi01232 Nucleotide metabolism 4
ghi01240 Biosynthesis of cofactors 4
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
bna00240 Pyrimidine metabolism 3
bna00670 One carbon pool by folate 3
bna00790 Folate biosynthesis 3
bna01232 Nucleotide metabolism 3
bna01240 Biosynthesis of cofactors 3
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
bna00240 Pyrimidine metabolism 2
bna00670 One carbon pool by folate 2
bna00790 Folate biosynthesis 2
bna01232 Nucleotide metabolism 2
bna01240 Biosynthesis of cofactors 2
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cre03030 DNA replication 9
cre03410 Base excision repair 5
cre03420 Nucleotide excision repair 5
cre03430 Mismatch repair 5
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
sbi03015 mRNA surveillance pathway 3
sbi04120 Ubiquitin mediated proteolysis 2
sbi03050 Proteasome 2
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
sot01200 Carbon metabolism 4
sot00010 Glycolysis / Gluconeogenesis 3
sot00020 Citrate cycle (TCA cycle) 3
sot00620 Pyruvate metabolism 3
sot00630 Glyoxylate and dicarboxylate metabolism 3
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
bdi03008 Ribosome biogenesis in eukaryotes 5
bdi00240 Pyrimidine metabolism 2
bdi01232 Nucleotide metabolism 2
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
nta04075 Plant hormone signal transduction 6
nta04626 Plant-pathogen interaction 6
nta04144 Endocytosis 3
nta00240 Pyrimidine metabolism 2
nta00670 One carbon pool by folate 2
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
nta04075 Plant hormone signal transduction 6
nta04626 Plant-pathogen interaction 6
nta04144 Endocytosis 3
nta00240 Pyrimidine metabolism 2
nta00670 One carbon pool by folate 2
Expression Expression pattern Expression pattern Expression pattern Expression pattern Expression pattern Expression pattern Expression pattern Expression pattern Expression pattern Expression pattern Expression pattern Expression pattern Expression pattern Expression pattern Expression pattern Expression pattern Expression pattern Expression pattern Expression pattern Expression pattern Expression pattern Expression pattern Expression pattern Expression pattern Expression pattern Expression pattern Expression pattern Expression pattern Expression pattern Expression pattern Expression pattern
Entrez Gene ID* 816134 829609 100786311 100786329 101267455 9271078 4350527 541707 100286018 103862355 103836808 100267529 100255872 7456362 7470002 11415341 25495385 123190811 123054960 123428176 107928896 107927990 106393759 106406829 5725986 8068714 102593228 102610005 100832991 107794251 107792811
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