ATTED-II : GeneCoexpression result

Select Species^**

Orthologous genes in OrthoFinder^**

Species	Gene	Description
vvi-u.5	METK4	S-adenosylmethionine synthetase 4
vvi-r.5	METK4	S-adenosylmethionine synthetase 4
vvi-m.5	METK4	S-adenosylmethionine synthetase 4
vvi-u.5	METK3	S-adenosylmethionine synthetase 3
vvi-u.5	METK2	S-adenosylmethionine synthetase 2
ath-u.5	MAT3	methionine adenosyltransferase 3
ath-u.5	MTO3	S-adenosylmethionine synthetase family protein
ath-u.5	SAM-2	S-adenosylmethionine synthetase 2
gma-u.5	100812341	S-adenosylmethionine synthase 1
gma-u.5	100816602	S-adenosylmethionine synthase 1
gma-u.5	100805448	S-adenosylmethionine synthase 3
bra-r.6	103836799	S-adenosylmethionine synthase
bra-r.6	103839308	S-adenosylmethionine synthase 2
bra-r.6	103849483	S-adenosylmethionine synthase 2
ppo-u.5	7495188	S-adenosylmethionine synthase 1-like
ppo-u.5	7478878	S-adenosylmethionine synthase 2-like
ppo-u.5	18100144	S-adenosylmethionine synthase 4-like
mtr-u.5	11444997	S-adenosylmethionine synthase
mtr-u.5	11432371	S-adenosylmethionine synthase 3
mtr-u.5	11435308	S-adenosylmethionine synthase-like
ghi-r.1	107911137	S-adenosylmethionine synthase 1
ghi-r.1	107910531	S-adenosylmethionine synthase
ghi-r.1	107908751	S-adenosylmethionine synthase 1
bna-r.1	125597747	S-adenosylmethionine synthase 3
bna-r.1	106451560	S-adenosylmethionine synthase 2
bna-r.1	106451494	S-adenosylmethionine synthase 3-like
cit-r.1	102607487	S-adenosylmethionine synthase 3
cit-r.1	102609114	S-adenosylmethionine synthase 2
cit-r.1	102618655	S-adenosylmethionine synthase
sly-u.5	101245012	S-adenosylmethionine synthase 3-like
sly-u.5	SAM1	S-adenosyl-L-methionine synthetase
sly-u.5	SAM3	S-adenosyl-L-methionine synthetase
sot-r.1	METK1	S-adenosylmethionine synthase 1-like
sot-r.1	102578902	S-adenosylmethionine synthase 2
sot-r.1	102591461	S-adenosylmethionine synthase 2
nta-r.1	107765217	S-adenosylmethionine synthase 1-like
nta-r.1	107766708	S-adenosylmethionine synthase 3-like
nta-r.1	107769520	S-adenosylmethionine synthase 1-like
osa-u.5	4326996	S-adenosylmethionine synthase 2-like
osa-u.5	4325163	S-adenosylmethionine synthase 3-like
osa-u.5	4337733	S-adenosylmethionine synthase 1-like
zma-u.5	100282324	S-adenosylmethionine synthetase 1
zma-u.5	100194360	S-adenosylmethionine synthase 1
zma-u.5	100191838	uncharacterized LOC100191838
tae-r.2	123078269	S-adenosylmethionine synthase 1
tae-r.2	123048309	S-adenosylmethionine synthase 2-like
tae-r.2	123061198	S-adenosylmethionine synthase 1
hvu-r.1	123405986	S-adenosylmethionine synthase 4
hvu-r.1	123405946	S-adenosylmethionine synthase 3
hvu-r.1	123406276	S-adenosylmethionine synthase 2-like
sbi-r.1	8060304	S-adenosylmethionine synthase 4
sbi-r.1	8071284	S-adenosylmethionine synthase 1
sbi-r.1	110433826	S-adenosylmethionine synthase 1
bdi-r.1	100844978	S-adenosylmethionine synthase 3
bdi-r.1	100824801	S-adenosylmethionine synthase 4
bdi-r.1	100843457	S-adenosylmethionine synthase 1
cre-r.1	CHLRE_06g250200v5	uncharacterized protein

Top 50 coexpressed genes to METK4 (vvi-u.5 coexpression data)

KEGG ID	Pathway name	#genes in coex list	#genes in genome	-log10(p)	Link to the KEGG^* map (Multiple genes)

Top 50 enrichment test to METK4 (vvi-u.5 coexpression data)

CoexMap"100251171"

[Cytoscape]

Annotation

functional annotation

KEGG

vvi00270 [list] [network] Cysteine and methionine metabolism (109 genes)

vvi00670 [list] [network] One carbon pool by folate (40 genes)

vvi00999 [list] [network] Biosynthesis of various plant secondary metabolites (85 genes)

vvi01230 [list] [network] Biosynthesis of amino acids (211 genes)

vvi01240 [list] [network] Biosynthesis of cofactors (226 genes)

GO BP

GO:0006556 [list] [network] S-adenosylmethionine biosynthetic process

(6 genes)

IEA

GO CC

GO:0005829 [list] [network] cytosol

(779 genes)

IEA

GO MF

GO:0004478 [list] [network] methionine adenosyltransferase activity	(5 genes)	IEA
GO:0005524 [list] [network] ATP binding	(2120 genes)	IEA

Protein

NP_001384672.1 [sequence] [blastp]

Subcellular
localization
wolf

cysk 6, cyto 4

(predict for NP_001384672.1)

Subcellular
localization
TargetP

other 8

(predict for NP_001384672.1)

Gene expression

All samples

[Expression pattern]

Tissue specificity^*

Coexpression

	Gene	Function	KEGG					Entrez Gene ID	Other ID	Link	Target			Reference
	Gene	Function	KEGG					Entrez Gene ID	Other ID	Link	vvi-u.5 for METK4	vvi-r.5 for METK4	vvi-m.5 for METK4	vvi-u.5 for METK3	vvi-u.5 for METK2	ath-u.5 for MAT3	ath-u.5 for MTO3	ath-u.5 for SAM-2	gma-u.5 for 100812341	gma-u.5 for 100816602	gma-u.5 for 100805448	bra-r.6 for 103836799	bra-r.6 for 103839308	bra-r.6 for 103849483	ppo-u.5 for 7495188	ppo-u.5 for 7478878	ppo-u.5 for 18100144	mtr-u.5 for 11444997	mtr-u.5 for 11432371	mtr-u.5 for 11435308	ghi-r.1 for 107911137	ghi-r.1 for 107910531	ghi-r.1 for 107908751	bna-r.1 for 125597747	bna-r.1 for 106451560	bna-r.1 for 106451494	cit-r.1 for 102607487	cit-r.1 for 102609114	cit-r.1 for 102618655	sly-u.5 for 101245012	sly-u.5 for SAM1	sly-u.5 for SAM3	sot-r.1 for METK1	sot-r.1 for 102578902	sot-r.1 for 102591461	nta-r.1 for 107765217	nta-r.1 for 107766708	nta-r.1 for 107769520	osa-u.5 for 4326996	osa-u.5 for 4325163	osa-u.5 for 4337733	zma-u.5 for 100282324	zma-u.5 for 100194360	zma-u.5 for 100191838	tae-r.2 for 123078269	tae-r.2 for 123048309	tae-r.2 for 123061198	hvu-r.1 for 123405986	hvu-r.1 for 123405946	hvu-r.1 for 123406276	sbi-r.1 for 8060304	sbi-r.1 for 8071284	sbi-r.1 for 110433826	bdi-r.1 for 100844978	bdi-r.1 for 100824801	bdi-r.1 for 100843457	cre-r.1 for CHLRE_06g250200v5

Ortholog

Ortholog ID: 562

Species

vvi

ath

gma

bra

ppo

mtr

ghi

bna

cit

sly

sot

nta

osa

zma

tae

hvu

sbi

bdi

cre

Symbol

METK4

METK2

METK5

MAT3

MTO3

SAM1

SAM3

SAM2

METK1

Function^*

S-adenosylmethionine synthetase 4

S-adenosylmethionine synthetase 2

S-adenosylmethionine synthetase 5

methionine adenosyltransferase 3

S-adenosylmethionine synthetase family protein

S-adenosylmethionine synthetase 1

S-adenosylmethionine synthase-like

S-adenosylmethionine synthase

S-adenosylmethionine synthase 1

S-adenosylmethionine synthase 2

S-adenosylmethionine synthase 3

S-adenosylmethionine synthase 1-like

S-adenosylmethionine synthase 2-like

S-adenosylmethionine synthase 3

S-adenosylmethionine synthase

S-adenosylmethionine synthase-like

S-adenosylmethionine synthase

S-adenosylmethionine synthase 2-like

S-adenosylmethionine synthase 2

S-adenosylmethionine synthase 3

S-adenosylmethionine synthase

S-adenosylmethionine synthase 1

S-adenosylmethionine synthase 3-like

S-adenosyl-L-methionine synthetase

S-adenosylmethionine synthase 2

S-adenosylmethionine synthase 1-like

S-adenosylmethionine synthase 2

S-adenosylmethionine synthase 2-like

S-adenosylmethionine synthase 1

S-adenosylmethionine synthase 2-like

S-adenosylmethionine synthase 3-like

S-adenosylmethionine synthase 1-like

S-adenosylmethionine synthase 1

uncharacterized LOC100191838

methionine adenosyltransferase

S-adenosylmethionine synthase 2

S-adenosylmethionine synthase 3

S-adenosylmethionine synthase

S-adenosylmethionine synthase 4

S-adenosylmethionine synthase 3

S-adenosylmethionine synthase 2

S-adenosylmethionine synthase 4

S-adenosylmethionine synthase 1

S-adenosylmethionine synthase 3

S-adenosylmethionine synthase 4

S-adenosylmethionine synthase 1

uncharacterized protein

Coexmap

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Coexpression

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KEGG Info

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
vvi00520	Amino sugar and nucleotide sugar metabolism	2

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
vvi00520	Amino sugar and nucleotide sugar metabolism	4
vvi01250	Biosynthesis of nucleotide sugars	4
vvi01240	Biosynthesis of cofactors	4
vvi00270	Cysteine and methionine metabolism	3
vvi00670	One carbon pool by folate	3

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
vvi00670	One carbon pool by folate	7
vvi00940	Phenylpropanoid biosynthesis	6
vvi01230	Biosynthesis of amino acids	5
vvi00260	Glycine, serine and threonine metabolism	4
vvi00630	Glyoxylate and dicarboxylate metabolism	4

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
ath00940	Phenylpropanoid biosynthesis	9
ath01230	Biosynthesis of amino acids	6
ath00270	Cysteine and methionine metabolism	5
ath00941	Flavonoid biosynthesis	4
ath00945	Stilbenoid, diarylheptanoid and gingerol biosynthesis	4

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
ath00940	Phenylpropanoid biosynthesis	7
ath01230	Biosynthesis of amino acids	6
ath00670	One carbon pool by folate	5
ath01240	Biosynthesis of cofactors	4
ath00270	Cysteine and methionine metabolism	4

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
gma00940	Phenylpropanoid biosynthesis	10
gma00941	Flavonoid biosynthesis	5
gma00945	Stilbenoid, diarylheptanoid and gingerol biosynthesis	5
gma00130	Ubiquinone and other terpenoid-quinone biosynthesis	4
gma00270	Cysteine and methionine metabolism	3

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
gma00670	One carbon pool by folate	8
gma01230	Biosynthesis of amino acids	7
gma01200	Carbon metabolism	6
gma01240	Biosynthesis of cofactors	6
gma00270	Cysteine and methionine metabolism	6

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
gma00670	One carbon pool by folate	7
gma01240	Biosynthesis of cofactors	6
gma00270	Cysteine and methionine metabolism	5
gma01230	Biosynthesis of amino acids	5
gma01200	Carbon metabolism	3

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
bra00520	Amino sugar and nucleotide sugar metabolism	5
bra01250	Biosynthesis of nucleotide sugars	5
bra00270	Cysteine and methionine metabolism	3
bra01230	Biosynthesis of amino acids	3
bra01240	Biosynthesis of cofactors	3

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
bra00270	Cysteine and methionine metabolism	5
bra01230	Biosynthesis of amino acids	5
bra00670	One carbon pool by folate	3
bra00999	Biosynthesis of various plant secondary metabolites	3
bra01240	Biosynthesis of cofactors	3

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
bra01230	Biosynthesis of amino acids	13
bra00270	Cysteine and methionine metabolism	11
bra00670	One carbon pool by folate	10
bra01240	Biosynthesis of cofactors	8
bra00999	Biosynthesis of various plant secondary metabolites	6

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
ppo00670	One carbon pool by folate	8
ppo01230	Biosynthesis of amino acids	5
ppo01240	Biosynthesis of cofactors	5
ppo01200	Carbon metabolism	4
ppo00940	Phenylpropanoid biosynthesis	4

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
ppo00270	Cysteine and methionine metabolism	11
ppo01230	Biosynthesis of amino acids	10
ppo00670	One carbon pool by folate	8
ppo01240	Biosynthesis of cofactors	6
ppo00450	Selenocompound metabolism	4

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
ppo01240	Biosynthesis of cofactors	5
ppo00520	Amino sugar and nucleotide sugar metabolism	4
ppo00230	Purine metabolism	4
ppo01230	Biosynthesis of amino acids	4
ppo00270	Cysteine and methionine metabolism	4

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
mtr01230	Biosynthesis of amino acids	9
mtr00270	Cysteine and methionine metabolism	8
mtr00670	One carbon pool by folate	8
mtr01240	Biosynthesis of cofactors	5
mtr01200	Carbon metabolism	4

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
mtr01230	Biosynthesis of amino acids	10
mtr00670	One carbon pool by folate	8
mtr00270	Cysteine and methionine metabolism	7
mtr01200	Carbon metabolism	5
mtr01240	Biosynthesis of cofactors	4

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
ghi00270	Cysteine and methionine metabolism	7
ghi00670	One carbon pool by folate	7
ghi00999	Biosynthesis of various plant secondary metabolites	7
ghi01230	Biosynthesis of amino acids	7
ghi01240	Biosynthesis of cofactors	7

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
ghi00270	Cysteine and methionine metabolism	7
ghi00670	One carbon pool by folate	7
ghi00999	Biosynthesis of various plant secondary metabolites	7
ghi01230	Biosynthesis of amino acids	7
ghi01240	Biosynthesis of cofactors	7

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
ghi00270	Cysteine and methionine metabolism	7
ghi00670	One carbon pool by folate	7
ghi00999	Biosynthesis of various plant secondary metabolites	7
ghi01230	Biosynthesis of amino acids	7
ghi01240	Biosynthesis of cofactors	7

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
bna00940	Phenylpropanoid biosynthesis	9
bna00130	Ubiquinone and other terpenoid-quinone biosynthesis	5
bna00941	Flavonoid biosynthesis	5
bna00945	Stilbenoid, diarylheptanoid and gingerol biosynthesis	5
bna00360	Phenylalanine metabolism	4

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
bna00270	Cysteine and methionine metabolism	9
bna00670	One carbon pool by folate	9
bna00999	Biosynthesis of various plant secondary metabolites	9
bna01230	Biosynthesis of amino acids	9
bna01240	Biosynthesis of cofactors	9

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
bna00270	Cysteine and methionine metabolism	9
bna00670	One carbon pool by folate	9
bna00999	Biosynthesis of various plant secondary metabolites	9
bna01230	Biosynthesis of amino acids	9
bna01240	Biosynthesis of cofactors	9

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
cit01230	Biosynthesis of amino acids	4
cit03010	Ribosome	4
cit00190	Oxidative phosphorylation	3
cit01210	2-Oxocarboxylic acid metabolism	3
cit00270	Cysteine and methionine metabolism	3

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
cit01230	Biosynthesis of amino acids	10
cit00270	Cysteine and methionine metabolism	5
cit00670	One carbon pool by folate	5
cit01240	Biosynthesis of cofactors	4
cit00260	Glycine, serine and threonine metabolism	4

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
cit00270	Cysteine and methionine metabolism	4
cit01230	Biosynthesis of amino acids	4
cit01200	Carbon metabolism	3
cit00940	Phenylpropanoid biosynthesis	3
cit00670	One carbon pool by folate	2

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
sly01230	Biosynthesis of amino acids	7
sly00270	Cysteine and methionine metabolism	5
sly01200	Carbon metabolism	4
sly01240	Biosynthesis of cofactors	4
sly00670	One carbon pool by folate	4

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
sly01230	Biosynthesis of amino acids	5
sly00670	One carbon pool by folate	4
sly00270	Cysteine and methionine metabolism	4
sly01200	Carbon metabolism	3
sly01240	Biosynthesis of cofactors	3

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
sly00920	Sulfur metabolism	8
sly01320	Sulfur cycle	6
sly01230	Biosynthesis of amino acids	3
sly01240	Biosynthesis of cofactors	3
sly00270	Cysteine and methionine metabolism	2

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
sot04120	Ubiquitin mediated proteolysis	3
sot03040	Spliceosome	2
sot03083	Polycomb repressive complex	2
sot04141	Protein processing in endoplasmic reticulum	2
sot01230	Biosynthesis of amino acids	2

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
sot00670	One carbon pool by folate	7
sot01240	Biosynthesis of cofactors	6
sot00270	Cysteine and methionine metabolism	6
sot01230	Biosynthesis of amino acids	5
sot01200	Carbon metabolism	4

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
sot00920	Sulfur metabolism	8
sot01320	Sulfur cycle	7
sot00230	Purine metabolism	3
sot00261	Monobactam biosynthesis	3
sot00450	Selenocompound metabolism	3

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
nta00270	Cysteine and methionine metabolism	8
nta01230	Biosynthesis of amino acids	8
nta00670	One carbon pool by folate	6
nta00999	Biosynthesis of various plant secondary metabolites	6
nta01240	Biosynthesis of cofactors	6

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
nta00270	Cysteine and methionine metabolism	6
nta00670	One carbon pool by folate	6
nta00999	Biosynthesis of various plant secondary metabolites	6
nta01230	Biosynthesis of amino acids	6
nta01240	Biosynthesis of cofactors	6

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
nta00270	Cysteine and methionine metabolism	8
nta01230	Biosynthesis of amino acids	8
nta00670	One carbon pool by folate	6
nta00999	Biosynthesis of various plant secondary metabolites	6
nta01240	Biosynthesis of cofactors	6

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
osa00940	Phenylpropanoid biosynthesis	8
osa01230	Biosynthesis of amino acids	5
osa00360	Phenylalanine metabolism	3
osa00270	Cysteine and methionine metabolism	3
osa00670	One carbon pool by folate	3

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
osa00270	Cysteine and methionine metabolism	2
osa01230	Biosynthesis of amino acids	2
osa00220	Arginine biosynthesis	2
osa00250	Alanine, aspartate and glutamate metabolism	2
osa01200	Carbon metabolism	2

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
osa00940	Phenylpropanoid biosynthesis	8
osa01230	Biosynthesis of amino acids	6
osa00270	Cysteine and methionine metabolism	4
osa00670	One carbon pool by folate	4
osa00360	Phenylalanine metabolism	3

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
zma01230	Biosynthesis of amino acids	9
zma00270	Cysteine and methionine metabolism	7
zma00940	Phenylpropanoid biosynthesis	6
zma00670	One carbon pool by folate	5
zma01240	Biosynthesis of cofactors	4

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
zma01230	Biosynthesis of amino acids	9
zma00270	Cysteine and methionine metabolism	6
zma00670	One carbon pool by folate	6
zma01240	Biosynthesis of cofactors	4
zma01200	Carbon metabolism	4

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
zma00270	Cysteine and methionine metabolism	6
zma01230	Biosynthesis of amino acids	6
zma00670	One carbon pool by folate	5
zma01240	Biosynthesis of cofactors	3
zma00450	Selenocompound metabolism	3

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
tae00270	Cysteine and methionine metabolism	13
tae00670	One carbon pool by folate	13
tae01230	Biosynthesis of amino acids	10
tae01240	Biosynthesis of cofactors	7
tae00999	Biosynthesis of various plant secondary metabolites	6

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
tae00670	One carbon pool by folate	14
tae00270	Cysteine and methionine metabolism	12
tae01230	Biosynthesis of amino acids	11
tae01240	Biosynthesis of cofactors	8
tae00999	Biosynthesis of various plant secondary metabolites	6

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
hvu01230	Biosynthesis of amino acids	2
hvu04148	Efferocytosis	2

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
hvu01230	Biosynthesis of amino acids	6
hvu00270	Cysteine and methionine metabolism	5
hvu00670	One carbon pool by folate	5
hvu01200	Carbon metabolism	4
hvu01240	Biosynthesis of cofactors	3

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
hvu01230	Biosynthesis of amino acids	7
hvu00270	Cysteine and methionine metabolism	6
hvu00670	One carbon pool by folate	6
hvu01240	Biosynthesis of cofactors	5
hvu00999	Biosynthesis of various plant secondary metabolites	3

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
sbi01230	Biosynthesis of amino acids	9
sbi00270	Cysteine and methionine metabolism	6
sbi00670	One carbon pool by folate	6
sbi01240	Biosynthesis of cofactors	4
sbi00999	Biosynthesis of various plant secondary metabolites	3

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
sbi01230	Biosynthesis of amino acids	8
sbi00270	Cysteine and methionine metabolism	6
sbi00670	One carbon pool by folate	6
sbi01240	Biosynthesis of cofactors	4
sbi00999	Biosynthesis of various plant secondary metabolites	3

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
sbi00940	Phenylpropanoid biosynthesis	11
sbi00360	Phenylalanine metabolism	7
sbi01230	Biosynthesis of amino acids	5
sbi00270	Cysteine and methionine metabolism	4
sbi00670	One carbon pool by folate	3

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
bdi01230	Biosynthesis of amino acids	5
bdi00670	One carbon pool by folate	5
bdi00270	Cysteine and methionine metabolism	4
bdi01240	Biosynthesis of cofactors	3
bdi00999	Biosynthesis of various plant secondary metabolites	2

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
bdi00020	Citrate cycle (TCA cycle)	4
bdi01200	Carbon metabolism	4
bdi01230	Biosynthesis of amino acids	4
bdi01210	2-Oxocarboxylic acid metabolism	3
bdi00190	Oxidative phosphorylation	2

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
bdi01230	Biosynthesis of amino acids	8
bdi00270	Cysteine and methionine metabolism	6
bdi00670	One carbon pool by folate	5
bdi00450	Selenocompound metabolism	3
bdi01240	Biosynthesis of cofactors	3

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
cre01230	Biosynthesis of amino acids	5
cre00270	Cysteine and methionine metabolism	5
cre00670	One carbon pool by folate	4
cre01200	Carbon metabolism	4
cre00260	Glycine, serine and threonine metabolism	3

Expression

Expression pattern

Entrez Gene ID^*

100251171

100244176

100243560

818260

821003

839501

100777009

100787994

100777770

103839308

103849483

103867247

7495188

7478878

7468135

11444997

11435308

25486640

107922739

107923999

107897154

106450450

106437889

125596940

102607487

102618655

102622739

101245012

544302

101247506

102588511

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Species	vvi	ath	gma	bra	ppo	mtr	ghi	bna	cit	sly	sot	nta	osa	zma	tae	hvu	sbi	bdi	cre
Paralog	5	3	3	3	3	3	3	3	3	3	3	3	3	3	3	3	3	3	1

Select Species**

Orthologous genes in OrthoFinder**

Top 50 coexpressed genes to METK4 (vvi-u.5 coexpression data)

Top 50 enrichment test to METK4 (vvi-u.5 coexpression data)

Select Species^**

Orthologous genes in OrthoFinder^**